dihydropyrimidine dehydrogenase

Objective To study the expression of thymidine phosphorylase ( TP), thymidylate synthase ( TS) and dihydropyrimidine dehydrogenase ( DPD) mRNA in breast cancer and its correlation with prognosis.

目的探讨乳腺癌组织中胸苷酸化酶（TP）、胸苷酸合成酶（TS）和二氢嘧啶脱氢酶（DPD）mRNA表达水平及其与预后的关系。

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OBJECTIVE: To provide the advances of the research in dihydropyrimidine dehydrogenase ( DPD) and thymidine kinase ( TK) and the significances of their applications in clinical tumor chemotherapy.

目的：了解二氢嘧啶脱氢酶（DPD）和胸腺嘧啶核苷激酶（TK）的研究现状和在临床肿瘤治疗中的意义。

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Aim: To investigate the difference between the mRNA levels of thymidine phosphorylase ( TP), thymidylate synthase ( TS), and dihydropyrimidine dehydrogenase ( DPD) between Chinese and North European breast cancer patients.

胸苷酸合成酶、胸腺嘧啶脱氧核苷磷酸化酶及二氟嘧啶脱氢酶的表达与乳腺癌预后的相关性目的：检测北欧和中国人乳癌患者TP、TS、DPD mRNA水平的差异。

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Advances in affects on dihydropyrimidine dehydrogenase enzyme on 5-fluorouracil clinical efficiency

DPD酶对5-FU临床疗效影响的研究进展

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The mRNA expressions and the clinical significance of thymidylate synthase and dihydropyrimidine dehydrogenase in colorectal carcinoma

胸苷酸合成酶mRNA和二氢嘧啶脱氢酶mRNA在结直肠癌中的表达及临床意义

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Expressions of thymidine phosphorylase, thymidylate synthase and dihydropyrimidine dehydrogenase in breast cancer and their correlations with prognosis

TS、TP及DPD的表达与乳腺癌生物学行为相关性的研究

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Value of Prediction of 5FU Treatment Efficacy with Determination of the Expression Levels of Thymidylate Synthase ( TS) and Dihydropyrimidine Dehydrogenase ( DPD) in the Tumor Cells

TS、DPD表达水平对5-FU疗效的预测价值

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Clinicopathologic and prognostic significance of thymidine phosphorylase and dihydropyrimidine dehydrogenase activity in human colorectal carcinoma

人结直肠癌组织中胸腺嘧啶核苷磷酸化酶和二氢嘧啶脱氢酶的活性变化及其意义

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Survey of the polymorphism of dihydropyrimidine dehydrogenase gene in the Han nationality population

汉族人群中二氢嘧啶脱氢酶基因多态性的初步研究

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Research Progress in Dihydropyrimidine Dehydrogenase Gene Detection and Guiding Chemotherapy

二氢嘧啶脱氢酶及其基因检测与指导化疗的研究进展

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Clinical study of dihydropyrimidine dehydrogenase activity on chemotherapy of esophageal carcinoma

二氢嘧啶脱氢酶活性在食管癌化疗中的临床研究

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Regulation of dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in gastrointestinal cancer cells treated with fluorouracil

氟尿嘧啶对胃肠道肿瘤细胞DPD和TP表达的影响

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Objective To probe the relationship between the chemosensitivity of 7 gastrointestinal cancer cell lines and the expression levels of metabolic enzymes of fluoropyrimidines including thymidylate synthase ( TS), thymidine phosphorylase ( TP), and dihydropyrimidine dehydrogenase ( DPD).

目的探讨氟尿嘧啶类药物代谢酶&胸苷酸合成酶（TS）、胸苷磷酸化酶（TP）和二氢嘧啶脱氢酶（DPD）表达水平与人胃肠道肿瘤细胞化疗敏感性的关系。

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Objective To investigate the relationships among the expression of thymidylate synthase ( TS), thymidine phosphorylase ( TP), and dihydropyrimidine dehydrogenase ( DPD) and the prognosis of breast cancer.

目的通过检测乳腺癌标本中胸苷酸合成酶（TS）、胸腺嘧啶脱氧核苷磷酸化酶（TP）、二氟嘧啶脱氢酶（DPD）表达情况，探讨乳腺癌的生物学行为与上述3个指标之间的相关性。

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Advance in dihydropyrimidine dehydrogenase and thymidine kinase influencing on the clinical therapy of pyrimidine chemotherapy drugs

二氢嘧啶脱氢酶和胸腺嘧啶核苷激酶的研究进展

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